SCHEMBL754056

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL553924	0.86	KLKB1 (0.48)	ALDH1A1KMT2AKDM4ENPSR1HPGD
	SCHEMBL27765053	0.82	NPSR1 (0.40)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL10290772	0.82	NPSR1 (0.42)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL756483	0.80	P4HTM (0.41)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL4677310	0.79	HDAC4 (0.54)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL6819068	0.78	FAAH (0.49)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL759556	0.78	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL23011570	0.78	MAPK1 (0.41)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL13351713	0.78	KLKB1 (0.43)	ALDH1A1MEN1KMT2AKDM4EMAPT
	SCHEMBL756599	0.77	NPSR1 (0.70)	ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.