Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 6/20 | 0.34 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567398 | 1.00 | ANPEP (0.38) | ANPEPCTSKCTSSCTSLCTSB | |
| SCHEMBL7544773 | 0.93 | CTSK (0.40) | CTSKCTSSCTSLCTSBMMP1 | |
| SCHEMBL7567257 | 0.93 | CTSK (0.40) | CTSKCTSSCTSLCTSBMMP1 | |
| SCHEMBL7541260 | 0.93 | CTSK (0.36) | CTSKCTSSCTSLCTSBMMP2 | |
| SCHEMBL7566320 | 0.93 | CTSK (0.36) | CTSKCTSSCTSLCTSBMMP2 | |
| SCHEMBL7538431 | 0.93 | CTSK (0.36) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7567053 | 0.93 | CTSK (0.36) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7541309 | 0.93 | ANPEP (0.40) | ANPEPCTSKCTSSCTSLCTSB | |
| SCHEMBL7538332 | 0.92 | CTSK (0.35) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7570937 | 0.92 | CTSK (0.35) | CTSKCTSSCTSLCTSBREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |