Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.36 |
| ▸ | CTSS | P25774 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566320 | 1.00 | CTSK (0.36) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7544773 | 0.95 | CTSK (0.40) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7567257 | 0.95 | CTSK (0.40) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7567053 | 0.94 | CTSK (0.36) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL7538431 | 0.94 | CTSK (0.36) | CTSKCTSSCTSLCTSBMAPT | |
| SCHEMBL7570937 | 0.93 | CTSK (0.35) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7538332 | 0.93 | CTSK (0.35) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7567398 | 0.93 | ANPEP (0.38) | CTSKCTSSCTSLCTSBLMNA | |
| SCHEMBL7540764 | 0.93 | ANPEP (0.38) | CTSKCTSSCTSLCTSBLMNA | |
| SCHEMBL7547045 | 0.91 | CTSK (0.39) | CTSKCTSSCTSLCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |