Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.53 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 6/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538483 | 0.91 | ITGB1 (0.50) | ITGB1ITGA4ITGA2ITGB7PYGL | |
| SCHEMBL7539254 | 0.89 | ITGB1 (0.44) | ITGB1ITGA4ITGA2ITGB7PYGL | |
| SCHEMBL7548629 | 0.84 | ITGB1 (0.55) | ITGB1ITGA4ITGA2ITGB7ITGA5 | |
| SCHEMBL7547233 | 0.81 | TAS1R3 (0.43) | ITGB1ITGA4ITGA2ITGB7PYGL | |
| SCHEMBL7539479 | 0.81 | ITGB1 (0.54) | ITGB1ITGA4ITGA5ITGB2ICAM1 | |
| SCHEMBL7545114 | 0.80 | ITGB2 (0.57) | ITGB1ITGA4ITGA2ITGB7ITGA5 | |
| SCHEMBL7544739 | 0.79 | ITGB2 (0.56) | ITGB1ITGA4ITGA2ITGB7ITGA5 | |
| SCHEMBL7542115 | 0.78 | TAAR1 (0.50) | ITGB1ITGA4ITGA2ITGB7ITGA5 | |
| SCHEMBL7540918 | 0.76 | FOLH1 (0.51) | ITGB1ITGA4ITGB7ITGA5 | |
| SCHEMBL7538826 | 0.76 | ITGB1 (0.53) | ITGB1ITGA4ITGA2ITGB7PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |