SCHEMBL7541196

SCHEMBL7541196

CO/N=C(\C(N)=O)c1ccccc1COc1cc(C)ccc1C

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.49
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 1/20 0.47
PARP1 P09874 1/20 0.41
AKR1C1 Q04828 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
TSHR P16473 1/20 0.40
TNF P01375 1/20 0.40
PKM P14618 1/20 0.40
CDK5 Q00535 1/20 0.40
KLF5 Q13887 1/20 0.40
CDK5R1 Q15078 1/20 0.40
NOD1 Q9Y239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2839948 1.00 HIF1A (0.49) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2839951 1.00 HIF1A (0.49) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7962502 0.91 HIF1A (0.52) HIF1AALDH1A1NPC1RAB9APARP1
SCHEMBL8369646 0.90 HIF1A (0.50) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL8369647 0.90 HIF1A (0.50) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
Potassium Ion SCHEMBL8622091 0.90 HIF1A (0.49) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
Potassium Ion SCHEMBL8622087 0.90 HIF1A (0.49) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7543562 0.90 HIF1A (0.50) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL54335 0.89 ALDH1A1 (0.46) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5360660 0.89 ALDH1A1 (0.46) HIF1AALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0936864-A1 FUNGICIDAL COMPOSITION COMPRISING AN ACYLAMINOBENZAMIDE (COMPOUND A) AND PROCESS FOR PREPARING COMPOUND A ZENECA LIMITED (GB) 1999-08-25 EP claimed
WO-1998019539-A1 FUNGICIDAL COMPOSITION COMPRISING AN ACYLAMINOBENZAMIDE (COMPOUND A) AND PROCESS FOR PREPARING COMPOUND A ZENECA LIMITED (GB) 1998-05-14 WO claimed
EP-1171437-A1 PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES Syngenta Limited (GB) 2002-01-16 EP disclosed
WO-2000063207-A1 PESTICIDAL INDAZOLE OR BENZOTRIAZOLE DERIVATIVES SYNGENTA LIMITED (GB) 2000-10-26 WO disclosed
EP-0936864-A1 FUNGICIDAL COMPOSITION COMPRISING AN ACYLAMINOBENZAMIDE (COMPOUND A) AND PROCESS FOR PREPARING COMPOUND A ZENECA LIMITED (GB) 1999-08-25 EP disclosed
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
EP-0617011-B1 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO (JP) 1999-01-20 EP disclosed
WO-1998019539-A1 FUNGICIDAL COMPOSITION COMPRISING AN ACYLAMINOBENZAMIDE (COMPOUND A) AND PROCESS FOR PREPARING COMPOUND A ZENECA LIMITED (GB) 1998-05-14 WO disclosed
CN-1036580-C Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1997-12-03 CN disclosed
EP-0596692-B1 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO (JP) 1997-06-04 EP disclosed
US-5627284-A Process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI & CO., LTD. (JP) 1997-05-06 US disclosed
EP-0741125-A1 Benzyl compounds and process for producing same SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed
US-5506358-A USEFUL AS AGRICULTURAL FUNGICIDES SHIONOGI & CO., LTD. (JP) 1996-04-09 US disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
US-5442063-A Agricultural fungicides SHIONOGI & CO., LTD. (JP) 1995-08-15 US disclosed
CN-1105356-A Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1995-07-19 CN disclosed
EP-0617011-A2 Process for producing alkoxyiminoacetamide compounds SHIONOGI & CO., LTD. (JP) 1994-09-28 EP disclosed
EP-0596692-A2 A process for producing (E)-alkoxyimino or hydroxyiminoacetamide compounds and intermediates therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 EP disclosed