Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7541202

CCC(=CC=Cc1ccc2c(c1)OCO2)C(N)=O.N

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GABRA1 P14867 3/20 0.53
GABRB2 P47870 3/20 0.53
GABRG2 P18507 2/20 0.53
GABRB3 P28472 2/20 0.53
GABRA3 P34903 2/20 0.53
GABRA2 P47869 2/20 0.53
TRPM8 Q7Z2W7 1/20 0.52
CYP3A4 P08684 2/20 0.51
KDM4E B2RXH2 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
TRPV1 Q8NER1 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28537375 0.87 CYP1A2 (0.59) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL27528164 0.86 GABRA1 (0.55) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL27574398 0.85 GABRA1 (0.56) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL18076267 0.84 HSD17B10 (0.52) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL28999908 0.80 HSD17B10 (0.63) CYP1A2HSD17B10GABRA1GABRB2TRPM8
SCHEMBL25283960 0.79 KDM4E (0.60) CYP1A2HSD17B10GABRA1GABRB2CYP3A4
SCHEMBL11550413 0.75 GABRA1 (0.50) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL11550403 0.75 GABRA1 (0.50) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL27738406 0.75 CYP1A2 (0.63) CYP1A2HSD17B10GABRA1GABRB2GABRG2
SCHEMBL25423911 0.75 HSD17B10 (0.72) CYP1A2HSD17B10GABRA1GABRB2GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789042-B1 Process for producing highly reactive low-viscosity modified phenolic resins KASHIMA OIL (JP) 2002-05-15 EP disclosed
US-6166131-A Highly reactive modified phenolic resin and molding material for electrical/electronic parts and semiconductor sealing material KASHIMA OIL CO., LTD. (JP) 2000-12-26 US disclosed
US-6034210-A CONDENSING A HEAVY OIL OR PITCH WITH 0.3 TO 10 MOL OF A PHENOL, 0.2 TO 9 MOL IN TERMS OF FORMALDEHYDE, OF A FORMALDEHYDE COMPOUND AND 0.01 TO 3.0 MOL OF AN ACID CATALYST KASHIMA OIL CO., LTD. (JP) 2000-03-07 US disclosed
US-5936010-A LOW MOISTURE ABSORPTION; SEMICONDUCTOR SEALERS KASHIMA OIL CO., LTD. (JP) 1999-08-10 US disclosed
EP-0859374-A2 Process for producing highly reactive modified phenolic resin, and molding material, material for electrical/electronic parts and semiconductor sealing material Kashima oil Co., Ltd. (JP) 1998-08-19 EP disclosed
US-5792826-A POLYCONDENSING A PETROLEUM HEAVY OIL OR PITCH, A FORMALDEHYDE POLYMER AND A PHENOL USING ACID CATALYST, REACTING RESULTANT POLYMER WITH A PHENOL TO LOWER MOLECULAR WEIGHT KASHIMA OIL CO. LTD. (JP) 1998-08-11 US disclosed
EP-0789042-A2 Process for producing highly reactive low-viscosity modified phenolic resins KASHIMA OIL COMPANY (JP) 1997-08-13 EP disclosed
US-5521259-A POLYCONDENSING A HEAVY PETROLEUM OIL WITH A FORMALDEHYDE POLYMER IN THE PRESENCE OF ACID CATALYST KASHIMA OIL CO., LTD. (JP) 1996-05-28 US disclosed
EP-0665249-A1 Process for producing highly reactive modified phenolic resin KASHIMA OIL CO., LTD (JP) 1995-08-02 EP disclosed