Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CTSD | P07339 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441141 | 0.88 | HSD17B10 (0.76) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| SCHEMBL28583726 | 0.88 | HSD17B10 (0.76) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| SCHEMBL1344559 | 0.88 | HSD17B10 (0.76) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| SCHEMBL11458656 | 0.88 | HSD17B10 (0.76) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Piperic Acid SCHEMBL11460093 | 0.84 | HSD17B10 (1.00) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Piperic Acid SCHEMBL29429112 | 0.84 | HSD17B10 (1.00) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Piperic Acid SCHEMBL288595 | 0.84 | HSD17B10 (1.00) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Piperic Acid SCHEMBL447578 | 0.84 | HSD17B10 (1.00) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Piperic Acid SCHEMBL11460092 | 0.84 | HSD17B10 (1.00) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 | |
| Fumaric Acid SCHEMBL635750 | 0.83 | HSD17B10 (0.82) | HSD17B10CYP1A2HDAC6GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250073217-A1 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-03-06 | — | — | US | disclosed |
| US-20250073217-A1 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-03-06 | — | — | US | disclosed |
| WO-2023133135-A3 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023133135-A2 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023133135-A2 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250073217-A1 | SMALL MOLECULE ADRENORECEPTOR ANTAGONISTS AND USES THEREOF | OPRL1, OPRK1, OPRM1 | HSD17B10 2540/4885CYP1A2 783/4885HDAC6 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.