Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.57 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546611 | 0.92 | ALOX5 (0.57) | ALOX5EPHX2DYRK1AALOX5APPPARD | |
| SCHEMBL7542575 | 0.91 | ALOX5 (0.56) | ALOX5EPHX2DYRK1AALOX5APPPARD | |
| SCHEMBL7542888 | 0.90 | DYRK1A (0.53) | ALOX5EPHX2DYRK1AALOX5APPPARD | |
| SCHEMBL7543772 | 0.90 | DYRK1A (0.53) | ALOX5EPHX2DYRK1AALOX5APAKR1B1 | |
| SCHEMBL7548069 | 0.87 | ALOX5 (0.62) | ALOX5EPHX2DYRK1AALOX5APNPC1 | |
| SCHEMBL7548333 | 0.87 | ALOX5 (0.62) | ALOX5EPHX2DYRK1AALOX5APPPARD | |
| SCHEMBL7548708 | 0.86 | DYRK1A (0.58) | ALOX5EPHX2DYRK1AAKR1B1NPC1 | |
| SCHEMBL7544391 | 0.86 | ALOX5 (0.61) | ALOX5EPHX2DYRK1AALOX5APNPC1 | |
| SCHEMBL7545407 | 0.85 | EPHX2 (0.66) | ALOX5EPHX2ALOX5APPPARDNPC1 | |
| SCHEMBL7541020 | 0.85 | DYRK1A (0.54) | ALOX5EPHX2DYRK1AAKR1B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |