Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541581 | 0.90 | ALOX5 (0.57) | DYRK1AALOX5EPHX2ALOX5APAKR1B1 | |
| SCHEMBL7542888 | 0.89 | DYRK1A (0.53) | DYRK1AALOX5EPHX2ALOX5APAKR1B1 | |
| SCHEMBL7541360 | 0.87 | ALOX5 (0.57) | DYRK1AALOX5EPHX2ALOX5AP | |
| SCHEMBL7551643 | 0.87 | ALOX5 (0.56) | ALOX5EPHX2ALOX5AP | |
| SCHEMBL7541264 | 0.86 | ALOX5 (0.58) | DYRK1AALOX5EPHX2ALOX5AP | |
| SCHEMBL7550204 | 0.86 | DYRK1A (0.56) | DYRK1AALOX5EPHX2ALOX5APCYP1A2 | |
| SCHEMBL7548708 | 0.85 | DYRK1A (0.58) | DYRK1AALOX5EPHX2AKR1B1AGPAT2 | |
| SCHEMBL7550272 | 0.84 | ALOX5 (0.53) | ALOX5EPHX2ALOX5AP | |
| SCHEMBL7544335 | 0.84 | ALOX5 (0.71) | ALOX5EPHX2ALOX5AP | |
| SCHEMBL7546611 | 0.82 | ALOX5 (0.57) | DYRK1AALOX5EPHX2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |