Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536023 | 0.94 | SCN9A (0.43) | SCN9ACACNA1C | |
| SCHEMBL8837676 | 0.83 | ACE (0.43) | — | |
| Hydrochloric Acid SCHEMBL7487323 | 0.82 | ACE (0.43) | — | |
| SCHEMBL10811657 | 0.79 | MAPT (0.40) | — | |
| SCHEMBL30954347 | 0.76 | CCKBR (0.60) | — | |
| SCHEMBL30044625 | 0.76 | CCKBR (0.60) | — | |
| SCHEMBL10736517 | 0.76 | CCKBR (0.60) | — | |
| SCHEMBL5698825 | 0.76 | CCKBR (0.60) | — | |
| SCHEMBL5672901 | 0.76 | CCKBR (0.60) | — | |
| SCHEMBL10814256 | 0.75 | AADAT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575503-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |
| US-4473575-A | ANGIOTENSIN INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| US-4410520-A | ANGIOTENSION CONVERTING ENZYME INGIBITOR, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |