Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4608263 | 0.87 | ACE (0.57) | ACEITGB3ITGA2B | |
| SCHEMBL14021754 | 0.87 | ACE (0.57) | ACEITGB3ITGA2B | |
| SCHEMBL6479977 | 0.86 | FOLH1 (0.62) | RENACEMAPK1ITGB3ITGA2B | |
| SCHEMBL3824374 | 0.86 | REN (0.71) | RENACEMAPK1 | |
| SCHEMBL17629479 | 0.86 | REN (0.71) | RENACEMAPK1 | |
| SCHEMBL19341935 | 0.86 | REN (0.71) | RENACEMAPK1 | |
| SCHEMBL21244275 | 0.86 | REN (0.71) | RENACEMAPK1 | |
| SCHEMBL3499528 | 0.86 | REN (0.71) | RENACEMAPK1 | |
| SCHEMBL4608329 | 0.85 | ITGB3 (0.58) | ACEITGB3ITGA2B | |
| SCHEMBL14021672 | 0.85 | ITGB3 (0.58) | ACEITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |