Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.64 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541894 | 1.00 | TDP1 (0.69) | TDP1KDM4EKMT2AATMPIK3CG | |
| SCHEMBL7541377 | 0.93 | TDP1 (0.70) | TDP1KDM4EKMT2AATMPIK3CG | |
| SCHEMBL7541368 | 0.93 | TDP1 (0.70) | TDP1KDM4EKMT2AATMPIK3CG | |
| SCHEMBL7540157 | 0.90 | TDP1 (0.73) | TDP1KDM4EKMT2AATMPIK3CG | |
| SCHEMBL7542053 | 0.85 | DRD3 (0.64) | TDP1KDM4EKMT2APIK3CGPIK3CD | |
| SCHEMBL7542047 | 0.85 | DRD3 (0.64) | TDP1KDM4EKMT2APIK3CGPIK3CD | |
| SCHEMBL7538965 | 0.84 | KDM4E (0.68) | TDP1KDM4EKMT2APIK3CGPIK3CD | |
| SCHEMBL7538969 | 0.84 | KDM4E (0.68) | TDP1KDM4EKMT2APIK3CGPIK3CD | |
| SCHEMBL7539630 | 0.83 | KDM4E (0.68) | KDM4EKMT2APIK3CGPIK3CDPIK3R1 | |
| SCHEMBL7539624 | 0.83 | KDM4E (0.68) | KDM4EKMT2APIK3CGPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | PHARMACEUTICAL INDUSTRY TECHNOLOGY | 2002-05-23 | — | — | US | claimed |
| US-6492373-B2 | FOR TREATMENT OF BACTERIAL INFECTIONS AND/OR RENAL CANCER DISEASES | PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (TW) | 2002-12-10 | — | — | US | disclosed |
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | PHARMACEUTICAL INDUSTRY TECHNOLOGY | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | ATP6V1B1, GLS, RCC2 | TDP1 4697/4885KDM4E 1113/4885KMT2A 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.