Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 4/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541860 | 0.94 | FOLH1 (0.39) | GAAMAPTHPGDRAB9ATP53 | |
| SCHEMBL7541062 | 0.94 | FOLH1 (0.39) | GAAMAPTHPGDRAB9ATP53 | |
| SCHEMBL7541814 | 0.94 | MAPK1 (0.38) | GAAMAPTHPGDRAB9AFPR2 | |
| SCHEMBL7542492 | 0.93 | MAPK1 (0.39) | FPR2MAPK1ALDH1A1LMNA | |
| SCHEMBL7545836 | 0.93 | MAPK1 (0.39) | FPR2MAPK1ALDH1A1LMNA | |
| SCHEMBL7540893 | 0.93 | GAA (0.40) | GAAMAPTHPGDRAB9ACTSS | |
| SCHEMBL7541671 | 0.92 | ANPEP (0.46) | RAB9AFPR2CTSSCTSKMMP3 | |
| SCHEMBL7538130 | 0.90 | MEN1 (0.41) | GAAMAPTFPR2MAPK1ALDH1A1 | |
| SCHEMBL7544683 | 0.90 | MAPT (0.45) | GAAMAPTHPGDRAB9ATP53 | |
| SCHEMBL7565424 | 0.89 | CTSK (0.40) | GAAMAPTHPGDRAB9ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |