Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541941 | 0.93 | GAA (0.41) | GAAHPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL7546420 | 0.90 | GAA (0.43) | GAAHPGDRAB9AMAPTKMT2A | |
| SCHEMBL7564315 | 0.87 | CTSK (0.40) | GAAHPGDRAB9AMAPTCTSS | |
| SCHEMBL7565424 | 0.87 | CTSK (0.40) | GAAHPGDRAB9AMAPTCTSS | |
| SCHEMBL7541860 | 0.87 | FOLH1 (0.39) | GAAHPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL7541814 | 0.87 | MAPK1 (0.38) | GAAHPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL7541062 | 0.87 | FOLH1 (0.39) | GAAHPGDRAB9AMAPTALDH1A1 | |
| SCHEMBL7541736 | 0.87 | MMP3 (0.42) | GAAHPGDRAB9AMAPTCA1 | |
| SCHEMBL7541982 | 0.87 | MMP3 (0.42) | GAAHPGDRAB9AMAPTCA1 | |
| SCHEMBL7545836 | 0.86 | MAPK1 (0.39) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |