Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541918 | 0.94 | CTSL (0.43) | CTSLITGB1ITGA4MMP2MMP3 | |
| SCHEMBL7538222 | 0.94 | CTSL (0.39) | CTSLITGB1ITGA4MMP2CTSK | |
| SCHEMBL7541917 | 0.93 | GRN (0.39) | P2RX7CTSLITGB1ITGA4CTSK | |
| SCHEMBL7545083 | 0.91 | P2RX7 (0.40) | P2RX7CTSLITGB1ITGA4MMP2 | |
| SCHEMBL7547038 | 0.91 | P2RX7 (0.40) | P2RX7CTSLITGB1ITGA4MMP2 | |
| SCHEMBL7548201 | 0.89 | CTSL (0.42) | P2RX7CTSLITGB1ITGA4MMP2 | |
| SCHEMBL7542750 | 0.89 | CTSL (0.39) | P2RX7CTSLITGB1ITGA4MMP2 | |
| SCHEMBL7540162 | 0.89 | ITGB1 (0.46) | ITGB1ITGA4MMP2ANPEPMAPK1 | |
| SCHEMBL7540159 | 0.89 | ITGB1 (0.46) | ITGB1ITGA4MMP2ANPEPMAPK1 | |
| SCHEMBL7541267 | 0.88 | P2RX7 (0.38) | P2RX7CTSLITGB1ITGA4MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |