Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218818 | 0.76 | MAPT (0.43) | KDM4EALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL30298128 | 0.76 | MAPT (0.43) | KDM4EALDH1A1TSHRHSD17B10CYP1A2 | |
| Dimethylcarbate SCHEMBL5668096 | 0.69 | MAPT (0.37) | KDM4EALDH1A1TSHRHSD17B10HTR5A | |
| SCHEMBL27461755 | 0.66 | GAA (0.60) | KDM4EALDH1A1TSHRHTR5A | |
| SCHEMBL27303285 | 0.66 | GAA (0.60) | KDM4EALDH1A1TSHRHTR5A | |
| SCHEMBL152963 | 0.65 | AHR (0.61) | HDAC3HTR5ACYP1A2 | |
| SCHEMBL949200 | 0.65 | NOTUM (0.38) | KEAP1KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL14472468 | 0.64 | KDM4E (0.34) | KEAP1KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL30319870 | 0.63 | MAOB (0.43) | CYP2C19HDAC3HTR5ACYP1A2CA12 | |
| SCHEMBL7280521 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492373-B2 | FOR TREATMENT OF BACTERIAL INFECTIONS AND/OR RENAL CANCER DISEASES | PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER (TW) | 2002-12-10 | — | — | US | disclosed |
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | PHARMACEUTICAL INDUSTRY TECHNOLOGY | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061895-A1 | 6-fluoro-1,4-dihydro-7-[4-(2-hydroxyiminoethyl)-1-piperazinyl]-4-oxoquinoline-3-carboxylic acid derivatives, their preparation and pharmaceutical compositions | ATP6V1B1, GLS, RCC2 | KEAP1 186/4885KDM4E 1113/4885PDPK1 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.