Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | AGPAT2 | O15120 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543368 | 0.91 | AGPAT2 (0.57) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7551347 | 0.88 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7541707 | 0.87 | MAPT (0.52) | MAPTSMN1; SMN2POLBTP53NPC1 | |
| SCHEMBL7550333 | 0.87 | MAPT (0.46) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7542952 | 0.85 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7550212 | 0.83 | RAB9A (0.51) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7543927 | 0.81 | MAPT (0.56) | MAPTSMN1; SMN2POLBTP53NPC1 | |
| SCHEMBL7543732 | 0.81 | AGPAT2 (0.58) | MAPTSMN1; SMN2POLBAGPAT2NPC1 | |
| SCHEMBL7544185 | 0.81 | MAPT (0.49) | MAPTSMN1; SMN2POLBAGPAT2TP53 | |
| SCHEMBL7545924 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2AGPAT2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |