SCHEMBL7544185

SCHEMBL7544185

COC(=O)Nc1ccc(OCc2nc3cc(F)ccc3o2)cc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.49
TP53 P04637 1/20 0.49
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
NPC1 O15118 1/20 0.47
CETP P11597 2/20 0.47
LMNA P02545 1/20 0.47
CEPT1 Q9Y6K0 1/20 0.46
AGPAT2 O15120 6/20 0.43
POLB P06746 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
FAAH O00519 1/20 0.42
KDR P35968 1/20 0.42
CSF1R P07333 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7551347 0.91 SMN1; SMN2 (0.47) MAPTTP53RAB9ASMN1; SMN2NPC1
SCHEMBL7550212 0.89 RAB9A (0.51) MAPTTP53RAB9ASMN1; SMN2NPC1
SCHEMBL7543368 0.88 AGPAT2 (0.57) MAPTTP53RAB9ASMN1; SMN2NPC1
SCHEMBL7543732 0.87 AGPAT2 (0.58) MAPTRAB9ASMN1; SMN2NPC1CETP
SCHEMBL7544976 0.86 AGPAT2 (0.58) MAPTTP53RAB9ASMN1; SMN2NPC1
SCHEMBL7545924 0.86 MAPT (0.47) MAPTRAB9ASMN1; SMN2NPC1CETP
SCHEMBL7545106 0.85 CEPT1 (0.42) MAPTTP53RAB9ALMNACEPT1
SCHEMBL7542952 0.84 SMN1; SMN2 (0.57) MAPTTP53RAB9ASMN1; SMN2NPC1
SCHEMBL7545883 0.83 CETP (0.50) MAPTRAB9ASMN1; SMN2NPC1CETP
SCHEMBL7542964 0.81 MAPT (0.56) MAPTTP53RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed