Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316990 | 0.79 | CXCR4 (0.56) | F2PRSS1MAPTHDAC1SMN1; SMN2 | |
| SCHEMBL7317672 | 0.75 | LMNA (0.58) | MAPTEPHX1SMN1; SMN2MEN1NPC1 | |
| SCHEMBL19242051 | 0.72 | F2 (0.61) | F2PRSS1MAPTHDAC1LTA4H | |
| SCHEMBL7320596 | 0.72 | GRM2 (0.39) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7312703 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2LTA4HMEN1NPC1RAB9A | |
| SCHEMBL7311884 | 0.72 | GRM2 (0.41) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7551967 | 0.70 | F2 (0.69) | F2PRSS1KDM4CMAPTHDAC1 | |
| SCHEMBL7317002 | 0.70 | NOS2 (0.48) | KDM4CEPHX1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19241691 | 0.69 | F2 (0.56) | F2PRSS1MAPTHDAC1LTA4H | |
| SCHEMBL19241982 | 0.68 | F2 (0.56) | F2PRSS1MAPTHDAC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927035-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-0927035-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998010763-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1998-03-19 | — | — | WO | disclosed |