Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL27878279 | 0.93 | TP53 (0.53) | — | |
| Diethylamine SCHEMBL27872306 | 0.86 | — | — | |
| Diethylamine SCHEMBL17220640 | 0.85 | TP53 (0.44) | — | |
| Diethylamine SCHEMBL28751414 | 0.79 | — | — | |
| Diethylamine SCHEMBL2887296 | 0.79 | — | — | |
| Diethylamine SCHEMBL11450107 | 0.78 | OPRM1 (0.48) | — | |
| Diethylamine SCHEMBL3558785 | 0.78 | — | — | |
| Diethylamine SCHEMBL7368833 | 0.78 | — | — | |
| Diethylamine SCHEMBL2698 | 0.78 | — | — | |
| Diethylamine SCHEMBL7130457 | 0.78 | TP53 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731350-A | Sulfhydryl compound containing beta-ester groups and acetyl-transferred synthesis method thereof | UNIV ZHEJIANG | 2012-10-17 | — | — | CN | claimed |
| CN-102690271-A | Preparation process for intermediate of Lamellarin H | HUAIHAI INST TECHNOLOGY | 2012-09-26 | — | — | CN | claimed |
| CN-102503883-A | Method for selectively preparing isoindoline-1-ketone derivative or isoquinoline-1-ketone derivative | UNIV SHANGHAI JIAOTONG | 2012-06-20 | — | — | CN | claimed |
| CN-102153751-B | Method for preparing hyperbranched polymer by continuous click chemistry | UNIV ZHEJIANG | 2012-05-30 | — | — | CN | claimed |
| CN-101357908-B | Preparation of dibenzothiazole disulfide and triphenylphosphine by one-pot method | UNIV ZHEJIANG TECHNOLOGY | 2012-05-23 | — | — | CN | claimed |
| CN-102408363-A | Synthesis method of busulfan | JIANGE CHEN | 2012-04-11 | — | — | CN | claimed |
| CN-101659675-B | Regeneration method of triphenylphosphine from waste residue of Wittig reaction | UNIV ZHEJIANG TECHNOLOGY | 2012-02-29 | — | — | CN | claimed |
| EP-0668269-B1 | Process for the sulfinylation of heterocyclic compounds | AVENTIS CROPSCIENCE SA (FR) | 2002-05-29 | — | — | EP | claimed |
| CN-105439171-B | Method for preparing SAPO-34 molecular sieve by using carbonate as synthesis accelerator and application thereof | 天津众智科技有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-105439171-A | Method for preparing SAPO-34 molecular sieve by using carbonate as synthesis prompting agent, and applications thereof | TIANJIN SIGMA INNOVA TECH CO LTD | 2016-03-30 | — | — | CN | disclosed |
| CN-101415717-B | Method for producing aldehyde using bisphosphite and group 8-10 metal compound, and such bisphosphite | KURARAY CO | 2012-12-12 | — | — | CN | disclosed |
| CN-102803256-A | Process for the preparation of -3- (3-fluoro-4- (1-methyl-5, 6-dihydro-1, 2, 4-triazin-4 (1H) -yl) phenyl) -5- (substituted methyl) oxazolidin-2-one derivatives | LEGOCHEM BIOSCIENCES INC | 2012-11-28 | — | — | CN | disclosed |
| CN-101336246-B | Phosphonic acid diester derivative and method for producing same | PING ZHURUN | 2012-11-28 | — | — | CN | disclosed |
| CN-102762635-A | Polyphenylene ether and method for producing same | ASAHI CHEMICAL CORP (JP) | 2012-10-31 | — | — | CN | disclosed |
| CN-102428075-A | Crystalline tripeptide epoxy ketone protease inhibitors | ONYX THERAPEUTICS INC | 2012-04-25 | — | — | CN | disclosed |
| CN-102408363-A | Synthesis method of busulfan | JIANGE CHEN | 2012-04-11 | — | — | CN | disclosed |
| CN-101659675-B | Regeneration method of triphenylphosphine from waste residue of Wittig reaction | UNIV ZHEJIANG TECHNOLOGY | 2012-02-29 | — | — | CN | disclosed |
| CN-102336758-A | Compound and combination as HCV polymerase inhibitors | PFIZER | 2012-02-01 | — | — | CN | disclosed |
| CN-101511827-B | Pyridin-4-yl derivatives as immunomodulating agents | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-02-01 | — | — | CN | disclosed |
| CN-102311371-A | Compound, polymer comprising the same and chemically amplified resist composition comprising the polymer | KOREA KUMHO PETROCHEM CO LTD | 2012-01-11 | — | — | CN | disclosed |