Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15325793 | 0.85 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL28230962 | 0.85 | ESR1 (0.38) | ESR1ESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL14367955 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL11932057 | 0.82 | ALDH1A1 (0.38) | ESR1ESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL12367664 | 0.79 | ESR1 (0.46) | ESR1ESR2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL15747030 | 0.78 | DAO (0.36) | ESR1ESR2MAPTARHSD11B1 | |
| SCHEMBL9505783 | 0.78 | ALDH1A1 (0.55) | ESR1ESR2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL296596 | 0.77 | ESR1 (0.44) | ESR1ESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL29540299 | 0.77 | ESR1 (0.44) | ESR1ESR2ALDH1A1KDM4EHPGD | |
| SCHEMBL26417533 | 0.76 | MEN1 (0.37) | ALDH1A1KDM4EHSD17B10CFTRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725284-B1 | Ocular lens material | MENICON CO LTD (JP) | 2002-05-22 | — | — | EP | disclosed |
| EP-0634673-B1 | Ocular lens material | MENICON CO LTD (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5703143-A | SILICON-CONTAINING POLYPHENYLENE ETHER POLYMER | MENICON CO., LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5605942-A | POLYIMIDE HAVING EXCELLENT TRANSPARENCY, OXYGEN PERMEABILITY, HEAT RESISTANCE, ULTRAVIOLET LIGHT ABSORPTION | MENICON CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0725284-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1996-08-07 | — | — | EP | disclosed |
| US-5543442-A | POLYIMIDESILOXANE COPOLYMER | MENICON CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0634673-A1 | Ocular lens material | Menicon Co., Ltd. (JP) | 1995-01-18 | — | — | EP | disclosed |