SCHEMBL296596

SCHEMBL296596

Nc1ccc(C(c2ccc(N)c(N)c2)(C(F)(F)F)C(F)(F)F)cc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
ALDH1A1 P00352 7/20 0.41
TDP1 Q9NUW8 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 3/20 0.38
PKM P14618 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
TSHR P16473 2/20 0.37
TP53 P04637 1/20 0.37
THRB P10828 1/20 0.37
NR4A1 P22736 1/20 0.36
PTPN5 P54829 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29540299 1.00 ESR1 (0.44) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL20869791 0.92 ESR1 (0.43) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL23836629 0.90 ESR1 (0.42) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL21122316 0.88 ALDH1A1 (0.42) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL27150221 0.87 TSHR (0.55) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL31345743 0.82 ESR2 (0.41) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL1352918 0.82 CYP3A4 (0.48) ESR1ESR2ALDH1A1TDP1KDM4E
SCHEMBL28567219 0.82 ESR2 (0.41) ESR1ESR2ALDH1A1TDP1MEN1
SCHEMBL295863 0.82 ESR1 (0.41) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL29464084 0.82 ESR1 (0.41) ESR1ESR2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 344 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297570-B1 2,2-BIS-(3-AMINOPHENYL)-HEXAFLUOROPROPANE DERIVATIVES AND PROCESS FOR THE PREPARATION OF 2,2-BIS-(3,4-DIAMINOPHENYL)-HEXAFLUOROPROPANE HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-05 EP claimed
US-4922019-A Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US claimed
EP-0297570-A2 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP claimed
JP-1029343-A None JP disclosed
JP-4227721-A None JP disclosed
WO-2026105370-A1 SHEET, METHOD FOR PRODUCING SHEET, AND CROSSLINKED RUBBER ARTICLE AGC株式会社 2026-05-21 WO disclosed
WO-2026105786-A1 FLUORINE-CONTAINING CROSSLINKED BODY AND METHOD FOR PRODUCING SAME, AND LAMINATE AND METHOD FOR MANUFACTURING SAME AGC株式会社 2026-05-21 WO disclosed
US-12583957-B2 Fluoropolymer-containing composition and molded article DAIKIN INDUSTRIES, LTD. (JP) 2026-03-24 US disclosed
EP-4253432-B1 FLUOROPOLYMER, AQUEOUS LIQUID DISPERSION, COMPOSITION, AND CROSSLINKED PRODUCT DAIKIN IND LTD (JP) 2026-02-25 EP disclosed
US-12559614-B2 Fluorinated copolymer composition and crosslinked rubber article AGC Inc. (JP) 2026-02-24 US disclosed
EP-4696743-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND CROSSLINKED RUBBER ARTICLE AGC Inc. (JP) 2026-02-18 EP disclosed
US-4922019-A Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
US-4922019-A Derivatives of 2,2-bis-(3-aminophenyl)hexafluoropropane and process for the preparation of 2,2-bis-(3,4-diaminophenyl)hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-01 US disclosed
EP-0297570-A2 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
EP-0297570-A2 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
EP-0297570-A2 2,2-Bis-(3-aminophenyl)-hexafluoropropane derivatives and process for the preparation of 2,2-bis-(3,4-diaminophenyl)-hexafluoropropane HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
EP-0084269-B1 RADIATION-SENSITIVE POLYIMIDE PRECURSOR COMPOSITION DERIVED FROM A DIARYL FLUORO COMPOUND E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-28 EP disclosed
US-4454220-A WITH POLYFUNCTIONAL ACRYLIC COMPOUND AND INITIATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-06-12 US disclosed
US-4430418-A AROMATIC POLYCARBOXYLIC COMPOUND, AND POLYFUNCTIONAL ACRYLATE COMPOUND WITH PROMOTER AND BIIMIDAZOLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-02-07 US disclosed
EP-0084269-A2 Radiation-sensitive polyimide precursor composition derived from a diaryl fluoro compound E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559614-B2 Fluorinated copolymer composition and crosslinked rubber article PFAS, FGB, PF4 ESR1 1031/4885ESR2 1580/4885ALDH1A1 4552/4885
US-12583957-B2 Fluoropolymer-containing composition and molded article AOC2, AOC1, AOC3 ESR1 1864/4885ESR2 1303/4885ALDH1A1 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.