Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543503 | 1.00 | MMP3 (0.45) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7539815 | 0.94 | FOLH1 (0.39) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7547273 | 0.94 | FOLH1 (0.45) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7547266 | 0.94 | FOLH1 (0.45) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7539811 | 0.94 | FOLH1 (0.39) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7542526 | 0.93 | MMP1 (0.39) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7542518 | 0.93 | MMP1 (0.39) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7543339 | 0.93 | MAPT (0.40) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7543337 | 0.93 | MAPT (0.40) | MMP3MMP2ACEMMECPA1 | |
| SCHEMBL7547049 | 0.92 | MMP1 (0.45) | MMP3MMP2MMP7MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |