Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19801506 | 1.00 | ATM (0.42) | ATMAKT1CES1CES2MAPT | |
| SCHEMBL3929546 | 0.86 | ATM (0.41) | ATMAKT1CES1CES2MAPT | |
| SCHEMBL3929544 | 0.86 | ATM (0.41) | ATMAKT1CES1CES2MAPT | |
| SCHEMBL18903903 | 0.81 | MAPT (0.40) | MAPTGPR52SMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL24488715 | 0.80 | ALDH1A1 (0.44) | MAPTLMNAKMT2ARAB9AMEN1 | |
| SCHEMBL28085607 | 0.78 | ATM (0.38) | ATMAKT1CES1CES2MAPT | |
| SCHEMBL18460837 | 0.78 | ATM (0.38) | ATMAKT1CES1CES2MAPT | |
| SCHEMBL13816475 | 0.76 | MAOA (0.36) | MAPTGPR52LMNAKMT2AMEN1 | |
| SCHEMBL21893465 | 0.76 | — | — | |
| SCHEMBL18560055 | 0.76 | SMN1; SMN2 (0.34) | ATMAKT1MAPTGPR52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | claimed |
| EP-1211284-A1 | Semi-finished products or moulded materials of improved toughness made from propylene polymers | Borealis GmbH (AT) | 2002-06-05 | — | — | EP | disclosed |
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | disclosed |
| EP-0884356-A2 | Blends of polyolefins and syndiotactic vinyl polymeres | PCD Polymere AG (AT) | 1998-12-16 | — | — | EP | disclosed |