Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 16/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835987 | 0.89 | PDE5A (0.60) | PDE5AKMT2A | |
| SCHEMBL3844228 | 0.85 | PDE5A (0.64) | PDE5AKDM4E | |
| SCHEMBL1263 | 0.83 | KMT2A (0.68) | PDE5AKMT2AKDM4E | |
| SCHEMBL3836990 | 0.82 | PDE5A (0.48) | PDE5A | |
| SCHEMBL845 | 0.82 | PDE5A (0.68) | PDE5AKMT2AKDM4E | |
| SCHEMBL7354844 | 0.81 | PDE5A (0.70) | PDE5A | |
| SCHEMBL6646508 | 0.81 | PDE5A (0.54) | PDE5AKMT2AKDM4E | |
| SCHEMBL6646139 | 0.81 | PDE5A (0.54) | PDE5AKMT2AKDM4E | |
| SCHEMBL31202676 | 0.81 | KMT2A (0.73) | PDE5AKMT2AKDM4E | |
| SCHEMBL1253 | 0.81 | KMT2A (0.73) | PDE5AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993006104-A1 | PYRAZOLOPYRIMIDINONE ANTIANGINAL AGENTS | PFIZER LIMITED (GB) | 1993-04-01 | — | — | WO | disclosed |