Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7198670 | 0.73 | MAPK14 (0.80) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL6654479 | 0.72 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL9117129 | 0.72 | MEN1 (0.45) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL7192115 | 0.71 | MAPK14 (0.77) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL11754533 | 0.70 | MAPK13 (0.56) | MAPK14MAPK13MAPK12MAPK11KMT2A | |
| SCHEMBL3821131 | 0.70 | LMNA (0.64) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL6655143 | 0.70 | MAPK14 (0.71) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL3822798 | 0.69 | RECQL (0.56) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL3825882 | 0.69 | LMNA (0.59) | MAPK14MAPK13MAPK12MAPK11RECQL | |
| SCHEMBL4707059 | 0.69 | RECQL (0.73) | MAPK14MAPK13MAPK12MAPK11RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002045752-A2 | DERMAL ANTI-INFLAMMATORY COMPOSITION | LEO PHARMA A/S (DK) | 2002-06-13 | — | — | WO | claimed |