Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119816 | 0.77 | KMT2A (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9119738 | 0.76 | EPAS1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29198073 | 0.74 | CYP2C9 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5383722 | 0.74 | KDM4E (0.54) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7042373 | 0.73 | ALDH1A1 (0.44) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28231888 | 0.73 | MAPT (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL25173362 | 0.72 | MAPT (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL30271403 | 0.72 | MAPT (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL9120775 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL7543757 | 0.72 | MAPK14 (0.56) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |