SCHEMBL7543767

SCHEMBL7543767

O=C(O)c1cc(Oc2ccc(O)cc2)cc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.52
LTA4H P09960 1/20 0.50
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
POLB P06746 3/20 0.48
BCL2 P10415 1/20 0.47
MCL1 Q07820 1/20 0.47
BAD Q92934 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
GFER P55789 1/20 0.45
GPR35 Q9HC97 1/20 0.44
DHODH Q02127 2/20 0.44
RXFP1 Q9HBX9 1/20 0.43
LDHA P00338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1162404 0.78 CDC25B (0.80) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL22129886 0.78 CDC25B (0.57) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL30182714 0.77 CDC25B (0.77) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL80302 0.77 CDC25B (0.77) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL10889935 0.76 CDC25B (0.78) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL27862583 0.76 MEN1 (0.58) CDC25BMCL1MEN1KMT2ANR4A1
SCHEMBL7535711 0.76 THRB (0.54) CDC25BLTA4HNR1H2BAXPOLB
SCHEMBL3308606 0.75 CDC25B (0.46) CDC25BMEN1KMT2AL3MBTL1NR4A1
Hydrochloric Acid SCHEMBL3914059 0.75 CDC25B (0.75) CDC25BPOLBMEN1KMT2ANR4A1
SCHEMBL27993309 0.75 POLB (0.65) LTA4HNR1H2BAXPOLBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 CDC25B 398/4885LTA4H 1285/4885NR1H2 3722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.