Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535815 | 1.00 | CES2 (0.47) | CES2KMT2AMAPTPLA2G4BDGKA | |
| SCHEMBL21100041 | 0.87 | KMT2A (0.52) | CES2KMT2AMAPTDGKACES1 | |
| SCHEMBL8567370 | 0.85 | CES2 (0.64) | CES2KMT2AMAPTPLA2G4BDGKA | |
| SCHEMBL11242983 | 0.85 | CES2 (0.64) | CES2KMT2AMAPTPLA2G4BDGKA | |
| SCHEMBL14614230 | 0.83 | CES2 (0.55) | CES2KMT2AMAPTPLA2G4BDGKA | |
| SCHEMBL5611964 | 0.82 | KMT2A (0.58) | CES2KMT2AMAPTDGKACES1 | |
| Dodecanoate SCHEMBL30912229 | 0.81 | GPR84 (0.65) | KMT2AMAPTALDH1A1MEN1PPARG | |
| Dodecanoate SCHEMBL29267330 | 0.81 | GPR84 (0.65) | KMT2AMAPTALDH1A1MEN1PPARG | |
| SCHEMBL26208623 | 0.81 | CES2 (0.50) | CES2KMT2AMAPTPLA2G4BDGKA | |
| SCHEMBL25885171 | 0.80 | CES2 (0.42) | CES2KMT2AMAPTPLA2G4BDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200454-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | Novuspharma S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009149-A1 | BISPLATINUM COMPLEXES ACTIVE THROUGH THE ORAL ROUTE | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |