Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MYOC | Q99972 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542125 | 1.00 | ACE (0.43) | ACEMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7542063 | 0.90 | GAA (0.40) | ACEMAPTNPSR1FPR2SMN1; SMN2 | |
| SCHEMBL7544141 | 0.90 | GAA (0.40) | ACEMAPTNPSR1FPR2SMN1; SMN2 | |
| SCHEMBL7541908 | 0.90 | MEN1 (0.44) | ACEMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7565475 | 0.90 | ACE (0.39) | ACEMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL7539858 | 0.90 | ACE (0.39) | ACEMAPTLMNAFPR2SMN1; SMN2 | |
| SCHEMBL7545839 | 0.90 | ACE (0.39) | ACEMAPTLMNAFPR2SMN1; SMN2 | |
| SCHEMBL7538838 | 0.90 | FPR2 (0.38) | ACEMAPTNPSR1LMNAFPR2 | |
| SCHEMBL7541658 | 0.90 | FPR2 (0.38) | ACEMAPTNPSR1LMNAFPR2 | |
| SCHEMBL7542841 | 0.89 | ACE (0.40) | ACEPPARGPPARALMNAFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |