Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547860 | 0.85 | REN (0.50) | REN | |
| SCHEMBL7562880 | 0.84 | CYP3A4 (0.32) | REN | |
| SCHEMBL7550731 | 0.81 | REN (0.64) | REN | |
| SCHEMBL7554961 | 0.71 | REN (0.51) | REN | |
| SCHEMBL7554357 | 0.69 | P2RX3 (0.30) | — | |
| SCHEMBL7546673 | 0.69 | REN (0.77) | REN | |
| SCHEMBL7569542 | 0.69 | REN (0.48) | REN | |
| SCHEMBL7562638 | 0.68 | REN (0.35) | REN | |
| SCHEMBL7549651 | 0.68 | REN (0.49) | REN | |
| SCHEMBL7436586 | 0.68 | REN (0.46) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |