Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23929052 | 0.96 | SLC6A4 (0.56) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8861866 | 0.86 | ALDH1A1 (0.66) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL7676221 | 0.84 | SIGMAR1 (0.56) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL3893675 | 0.84 | SLC6A4 (0.62) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL28343455 | 0.84 | SLC6A4 (0.55) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL27690554 | 0.82 | GRIN2B (0.59) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL5326826 | 0.82 | HRH3 (0.51) | GRIN2BGRIN2DGRIN3BADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL11024728 | 0.82 | MAPT (0.60) | SLC6A3SLC6A4GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8491361 | 0.81 | ALDH1A1 (0.61) | SLC6A3SLC6A4ALDH1A1KMT2AMAPT | |
| SCHEMBL28686898 | 0.80 | SMN1; SMN2 (0.62) | SLC6A3ADRA1AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040023-A1 | NOVEL USE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-05-23 | — | — | WO | disclosed |