Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | RGS12 | O14924 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468337 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7352888 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7285741 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7296911 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4179085 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17275126 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1448490 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1162502 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3468673 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1703575 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885886-B1 | PYRIDINECARBOXAMIDE DERIVATIVES | NISSHIN SEIFUN GROUP INC (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-5972943-A | N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0885886-A1 | NOVEL PYRIDINECARBOXAMIDE DERIVATIVES | Nisshin Flour Milling Co., Ltd. (JP) | 1998-12-23 | — | — | EP | disclosed |