Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | RGS12 | O14924 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468337 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7544499 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7352888 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7285741 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7296911 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4179085 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17275126 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1448490 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1162502 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1703575 | 1.00 | KDM4E (0.70) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261662-B1 | Novel synthetic blocking reagents | FORSCHUNGSZENTRUM BORSTEL LEIBNIZ ZENTRUM FUER MEDIZIN UND BIOWISSENSCHAFTEN (DE) | 2014-01-22 | — | — | EP | disclosed |
| US-8501199-B2 | Synthetic blocking reagents | FORSCHUNGSZENTRUM BORSTEL (DE) | 2013-08-06 | — | — | US | disclosed |
| US-20100317048-A1 | NOVEL SYNTHETIC BLOCKING REAGENTS | FORSCHUNGSZENTRUM BORSTEL (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2261662-A1 | Novel synthetic blocking reagents | Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften (DE) | 2010-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317048-A1 | NOVEL SYNTHETIC BLOCKING REAGENTS | SPR, SSB, LY96 | KDM4E 1490/4885ALDH1A1 3115/4885MEN1 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.