Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23532019 | 0.79 | TP53 (0.39) | MEN1MAPTKMT2AKCNN4KCNA3 | |
| SCHEMBL7538752 | 0.79 | KCNN4 (0.36) | MAPTKCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL5363164 | 0.79 | TRPA1 (0.39) | KCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL3152998 | 0.79 | TSHR (0.39) | KCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL27247249 | 0.78 | MAPT (0.43) | ATMMEN1MAPTKMT2AKCNN4 | |
| SCHEMBL7544520 | 0.76 | TDP1 (0.42) | MEN1KMT2AKCNN4KCNA3CYP11B1 | |
| SCHEMBL1195324 | 0.75 | AKR1B1 (0.44) | MAPTKDM4E | |
| SCHEMBL13539077 | 0.75 | KCNN4 (0.31) | KCNN4KCNA3CYP11B1CYP11B2 | |
| SCHEMBL3152490 | 0.75 | L3MBTL1 (0.32) | KCNN4KCNA3CYP11B1CYP11B2TDP1 | |
| SCHEMBL10814483 | 0.75 | IDO1 (0.44) | KCNN4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468995-B1 | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0667868-B1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |