Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785831 | 0.82 | HDAC1 (0.45) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL7574539 | 0.81 | ESR1 (0.44) | MEN1KMT2AESR1ESR2AOC3 | |
| SCHEMBL18811502 | 0.79 | MEN1 (0.32) | MEN1CYP1A2KMT2AESR1ESR2 | |
| SCHEMBL19997500 | 0.79 | HDAC1 (0.32) | MEN1CYP1A2KMT2AESR1ESR2 | |
| SCHEMBL21169892 | 0.78 | ESR1 (0.33) | MEN1CYP1A2KMT2AESR1ESR2 | |
| SCHEMBL2263489 | 0.78 | NR1I2 (0.42) | MEN1CYP1A2KMT2AESR1ESR2 | |
| SCHEMBL20402669 | 0.78 | GRIK2 (0.32) | MEN1CYP1A2KMT2AESR1ESR2 | |
| SCHEMBL1475613 | 0.76 | CES2 (0.48) | — | |
| SCHEMBL10799993 | 0.74 | ESR1 (0.39) | MEN1KMT2AESR1ESR2AOC3 | |
| SCHEMBL28121057 | 0.74 | LMNA (0.50) | CYP1A2ESR1ESR2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945420-B1 | Process for the preparation of bisphenols | MITSUI CHEMICALS INC (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6316677-B1 | REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION | MITSUI CHEMICALS, INC. (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-0945420-A1 | Process for the preparation of bisphenols | Mitsui Chemicals, Inc. (JP) | 1999-09-29 | — | — | EP | disclosed |