SCHEMBL754481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27534143	0.72	CSF1R (0.47)	SMN1; SMN2NPC1RAB9AALDH1A1CSF1R
	SCHEMBL27534146	0.72	CSF1R (0.47)	SMN1; SMN2NPC1RAB9AKDM4EALDH1A1
	SCHEMBL4060937	0.71	CSF1R (0.58)	SMN1; SMN2NPC1RAB9AALDH1A1CSF1R
	SCHEMBL29963496	0.70	KMT2A (0.71)	SMN1; SMN2GAANPC1RAB9AKDM4E
	SCHEMBL17183464	0.70	SMN1; SMN2 (1.00)	SMN1; SMN2GAARAB9AKDM4EALDH1A1
	SCHEMBL31675012	0.69	GAA (0.61)	SMN1; SMN2GAAKDM4EALDH1A1HPGD
	SCHEMBL2072047	0.69	CA12 (0.55)	SMN1; SMN2GAANPC1RAB9AKDM4E
	SCHEMBL13200785	0.69	MAPK14 (0.54)	SMN1; SMN2GAANPC1RAB9AKDM4E
	SCHEMBL13688113	0.69	RAB9A (0.53)	SMN1; SMN2GAANPC1RAB9AKDM4E
	SCHEMBL655554	0.69	NPC1 (0.59)	SMN1; SMN2GAANPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.