Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 3/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539228 | 1.00 | CTSL (0.34) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7544874 | 1.00 | CTSL (0.34) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7539234 | 1.00 | CTSL (0.34) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7541133 | 0.95 | MMP2 (0.39) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7542670 | 0.95 | MMP2 (0.39) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7542683 | 0.95 | MMP2 (0.39) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7541125 | 0.95 | MMP2 (0.39) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7544707 | 0.94 | MMP2 (0.37) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7541724 | 0.94 | MMP2 (0.37) | CTSLCTSBMMP2ITGB1ITGA4 | |
| SCHEMBL7541735 | 0.94 | MMP2 (0.37) | CTSLCTSBMMP2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |