Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546790 | 0.95 | HDAC2 (0.40) | FFAR4PTGDR2HDAC3HDAC4HDAC1 | |
| SCHEMBL7293971 | 0.80 | TDP1 (0.41) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL2532490 | 0.80 | LMNA (0.41) | ADRA1ASLC6A3SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7541400 | 0.80 | PTGDR2 (0.46) | FFAR4PTGDR2MMP14MAPTRXFP1 | |
| SCHEMBL27034290 | 0.79 | FFAR4 (0.42) | FFAR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14521051 | 0.78 | MEN1 (0.43) | PTGDR2SMN1; SMN2MAPTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9554758 | 0.78 | FFAR4 (0.41) | FFAR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2677344 | 0.76 | MMP14 (0.55) | FFAR4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2425306 | 0.76 | MEN1 (0.44) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL12451598 | 0.76 | MEN1 (0.38) | MAPK1ADRA1ASLC6A3SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211239-A1 | PROCESS FOR THE PREPARATION OF 2,3-DIHYDROAZEPINE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2002-06-05 | — | — | EP | disclosed |