Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7540519 | 0.79 | KDM4E (0.40) | MAPTALDH1A1TDP1SMN1; SMN2KDM4E | |
| SCHEMBL603951 | 0.76 | MAPT (0.58) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL27919545 | 0.74 | SMN1; SMN2 (0.62) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL7544926 | 0.73 | HPGD (0.51) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL3564375 | 0.73 | ALDH1A1 (0.48) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL27901818 | 0.70 | CTSS (0.51) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL26659404 | 0.70 | SCN9A (0.53) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL18015624 | 0.67 | ALDH1A1 (0.45) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL16939633 | 0.66 | ALDH1A1 (0.50) | MAPTHPGDALDH1A1TDP1LMNA | |
| SCHEMBL22064956 | 0.66 | KDM4E (0.67) | MAPTHPGDALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440984-B1 | PROTECTION FOR GROWING AND HARVESTED CROPS; CONTROLLING TOBACCO BUDWORMS AND SOUTHERN ARMYWORMS; PESTICIDES; INSECTICIDES; MITICIDES; ANTHELMINTICS | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-27 | — | — | US | disclosed |
| US-20020045634-A1 | Use of aryl-substituted pyrimidines as insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY | 2002-04-18 | — | — | US | disclosed |
| US-6306866-B1 | 2-ALKOXY SUBSTITUTED PYRIMIDINE DERIVATIVES | AMERICAN CYANAMID COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6153619-A | Aryl-substituted pyrimidines as insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 2000-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045634-A1 | Use of aryl-substituted pyrimidines as insecticidal and acaricidal agents | YBX1, YBX3, CYP1B1 | MAPT 3868/4885HPGD 3524/4885ALDH1A1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.