Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756945 | 0.94 | LMNA (0.38) | CA12CA1CA2CA4CA9 | |
| SCHEMBL754506 | 0.89 | MAPK1 (0.36) | CA1CA2LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL756576 | 0.80 | TDP1 (0.39) | LMNAL3MBTL1ALDH1A1BMP1 | |
| SCHEMBL25933085 | 0.66 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2L3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL25876065 | 0.64 | TSHR (0.39) | CA12CA1CA2CA4CA9 | |
| SCHEMBL18101226 | 0.64 | LMNA (0.57) | LMNAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL24918920 | 0.63 | MEN1 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL24918878 | 0.63 | MEN1 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL25746260 | 0.63 | MEN1 (0.42) | CA12CA1CA2CA4CA9 | |
| SCHEMBL15515951 | 0.63 | SMN1; SMN2 (0.52) | CA1CA2CA4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138272-B2 | Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds | ELAN PHARMACEUTICALS, INC. (US) | 2012-03-20 | — | — | US | disclosed |