SCHEMBL7545030

SCHEMBL7545030

COCCc1nc2c(N)nc3ccccc3c2n1CCCC[N+]1(c2ccc(C(N)=O)cc2)C=CC=C1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.54
TLR8 Q9NR97 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5747599 0.81 TLR7 (0.60) TLR7TLR8
SCHEMBL20806194 0.80 TLR7 (0.61) TLR7TLR8
SCHEMBL3869883 0.79 TLR7 (0.52) TLR7TLR8
SCHEMBL1950333 0.79 TLR7 (0.62) TLR7TLR8
SCHEMBL3865268 0.78 TLR7 (0.66) TLR7TLR8
SCHEMBL1951894 0.78 TLR7 (0.77) TLR7TLR8
SCHEMBL5747604 0.78 TLR7 (0.61) TLR7TLR8
SCHEMBL22522221 0.78 TLR7 (0.61) TLR7TLR8
SCHEMBL3873131 0.78 TLR7 (0.65) TLR7TLR8
SCHEMBL13937528 0.78 TLR7 (0.63) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187613-A4 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP disclosed
EP-1187613-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-03-20 EP disclosed
WO-2000076505-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed