Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971279 | 0.92 | VDR (0.57) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL19988240 | 0.90 | VDR (0.60) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL232217 | 0.86 | MAPT (0.74) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL8003899 | 0.86 | MAPT (0.74) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL10034122 | 0.86 | MAPT (0.74) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL4922329 | 0.86 | VDR (0.67) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL7096828 | 0.86 | VDR (0.67) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL7142687 | 0.86 | MEN1 (0.76) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL5539237 | 0.86 | MEN1 (0.76) | VDRMAPTMEN1KMT2AADORA3 | |
| SCHEMBL7518542 | 0.85 | VDR (0.61) | VDRMAPTMEN1KMT2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002045704-A2 | PREVENTION AND TREATMENT OF TACHYPHYLACTIC RESPONSE | MOLECULAR SKINCARE LIMITED (GB) | 2002-06-13 | — | — | WO | disclosed |
| EP-0969849-A1 | STABLE SOLID PREPARATION CONTAINING VITAMIN D3 AND TRICALCIUM PHOSPHATE | MERCK PATENT GmbH (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998040085-A1 | STABLE SOLID PREPARATION CONTAINING VITAMIN D3 AND TRICALCIUM PHOSPHATE | MERCK PATENT GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |
| US-4292249-A | VITAMIN D3 INTERMEDIATES | TEIJIN LIMITED (JP) | 1981-09-29 | — | — | US | disclosed |
| EP-0015122-A1 | New 25-hydroxy-24-oxocholestane derivatives and preparation thereof | TEIJIN LIMITED (JP) | 1980-09-03 | — | — | EP | disclosed |