Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CDC25A | P30304 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545052 | 0.92 | VDR (0.56) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL8003899 | 0.87 | MAPT (0.74) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL4922329 | 0.87 | VDR (0.67) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL10034122 | 0.87 | MAPT (0.74) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL7096828 | 0.87 | VDR (0.67) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL232217 | 0.87 | MAPT (0.74) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL11524819 | 0.85 | MAPT (0.61) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL11524817 | 0.85 | MAPT (0.61) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL5614119 | 0.85 | VDR (0.50) | VDRMEN1KMT2AMAPTCDC25A | |
| SCHEMBL6403771 | 0.85 | MAPT (0.75) | VDRMEN1KMT2AMAPTCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696275-A1 | VITAMIN D AMIDE DERIVATIVES | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY (US) | 1996-02-14 | — | — | EP | claimed |
| WO-1994026707-A1 | VITAMIN D AMIDE DERIVATIVES | HOLMES, MICHAEL, JOHN (GB) | 1994-11-24 | — | — | WO | claimed |