Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 15/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.58 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.58 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545062 | 1.00 | PTGS1 (0.58) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| SCHEMBL28020964 | 0.83 | HPGD (0.44) | PTGS1PTGS2MT-CO1MT-CO2 | |
| Mexoprofen SCHEMBL2111806 | 0.83 | PTGS1 (0.47) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| Mexoprofen SCHEMBL11858696 | 0.83 | PTGS1 (0.47) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| SCHEMBL11468007 | 0.78 | APP (0.64) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| SCHEMBL28874197 | 0.78 | PTGS1 (0.43) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| SCHEMBL2436189 | 0.78 | APP (0.56) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| Hexaprofen SCHEMBL2111016 | 0.77 | APP (0.67) | PTGS1PTGS2MT-CO1MT-CO2OPRK1 | |
| SCHEMBL11428636 | 0.75 | APP (0.51) | PTGS1PTGS2MT-CO1MT-CO2APP | |
| SCHEMBL59197 | 0.74 | PTGS2 (0.74) | PTGS1PTGS2LMNACYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002047661-A1 | PHARMACEUTICAL COMPOSITION FOR INTRAMUSCULAR INJECTION CONTAINING LOXOPROFEN | SHIN POONG PHARMACEUTICAL CO., LTD. (KR) | 2002-06-20 | — | — | WO | disclosed |