Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500100 | 0.94 | SSTR4 (0.34) | SSTR4 | |
| SCHEMBL27478681 | 0.94 | SSTR4 (0.34) | SSTR4 | |
| SCHEMBL8179292 | 0.87 | SSTR4 (0.33) | SSTR4 | |
| SCHEMBL4158496 | 0.85 | SSTR4 (0.38) | SSTR4 | |
| SCHEMBL1965746 | 0.72 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL7498467 | 0.72 | DUT (0.33) | SSTR4 | |
| SCHEMBL27478289 | 0.72 | DUT (0.33) | SSTR4 | |
| SCHEMBL1280544 | 0.71 | L3MBTL1 (0.33) | SSTR4 | |
| SCHEMBL17602961 | 0.70 | SSTR4 (0.38) | SSTR4 | |
| SCHEMBL6994755 | 0.69 | S1PR3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448247-B1 | TACHYKININ RECEPTOR ANTAGONIST; ESPECIALLY TO THE RECEPTORS FOR SUBSTANCE P (WHICH RECEPTORS ARE GENERALLY REFERRED TO AS ?NEUROKININ 1 RECEPTORS?) | SANKYO COMPANY, LIMITED (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-0776893-B1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO CO (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-6159967-A | Heterocyclic compounds having tachykinin receptor antagonist activity their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0776893-A1 | Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 | SANKYO COMPANY LIMITED (JP) | 1997-06-04 | — | — | EP | disclosed |