Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545655 | 0.84 | NOS1 (0.36) | PPIANOS1 | |
| SCHEMBL7547747 | 0.76 | ESR1 (0.39) | PPIANOS1 | |
| SCHEMBL18071836 | 0.76 | CNR1 (0.34) | BCHECNR1CNR2 | |
| SCHEMBL7542757 | 0.73 | KDM4E (0.30) | — | |
| Hydrochloric Acid SCHEMBL9820644 | 0.68 | PPIA (0.41) | PPIABCHE | |
| SCHEMBL9820926 | 0.67 | PPIA (0.45) | PPIASIGMAR1BCHE | |
| SCHEMBL21252533 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL9820718 | 0.66 | PPIA (0.44) | PPIASIGMAR1BCHE | |
| SCHEMBL18071852 | 0.65 | PARP1 (0.32) | PPIANOS1BCHE | |
| SCHEMBL11615288 | 0.65 | ESR2 (0.37) | PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900228-B1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | DOW CHEMICAL CO (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0900228-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041134-A1 | A METHOD FOR PRODUCING OCTAHYDROFLUORENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 1997-11-06 | — | — | WO | disclosed |
| US-5670680-A | Method for producing octahydrofluorenyl metal complexes | THE DOW CHEMICAL COMPANY (US) | 1997-09-23 | — | — | US | disclosed |