Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9820718 | 0.98 | PPIA (0.44) | PPIAHTR1ASIGMAR1BCHEACHE | |
| Hydrochloric Acid SCHEMBL9820644 | 0.87 | PPIA (0.41) | PPIABCHEACHEMEN1KMT2A | |
| SCHEMBL10698420 | 0.76 | PPIA (0.52) | PPIAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11615288 | 0.76 | ESR2 (0.37) | PPIAHTR1ADRD2DRD4DRD3 | |
| SCHEMBL10408026 | 0.76 | PPIA (0.49) | PPIAACHESLC6A2SLC6A4CYP2D6 | |
| SCHEMBL10698583 | 0.73 | PPIA (0.49) | PPIAMEN1KMT2AALDH1A1 | |
| SCHEMBL10407009 | 0.73 | PPIA (0.46) | PPIAACHESLC6A2SLC6A4HTT | |
| SCHEMBL9820917 | 0.71 | HTR1A (0.45) | HTR1ASIGMAR1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9820712 | 0.70 | HTR1A (0.44) | HTR1ASIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL12813351 | 0.69 | PPIA (0.47) | PPIABCHEACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | claimed |