Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.43 |
| ▸ | ITGAL | P20701 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7541018 | 0.93 | KMT2A (0.45) | ITGB2ICAM1ITGALHDAC8HDAC3 | |
| SCHEMBL7542032 | 0.92 | FPR2 (0.41) | ITGB2ICAM1ITGALHDAC8HDAC3 | |
| SCHEMBL7538530 | 0.92 | ITGB2 (0.48) | ITGB2ICAM1ITGALTP53POLB | |
| SCHEMBL7549315 | 0.91 | ITGB2 (0.42) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7540780 | 0.89 | ITGB2 (0.45) | ITGB2ICAM1ITGALPOLBKDM4E | |
| SCHEMBL7547460 | 0.89 | ITGB2 (0.56) | ITGB2ICAM1ITGALTP53POLB | |
| SCHEMBL7544812 | 0.89 | ITGB2 (0.56) | ITGB2ICAM1ITGALTP53POLB | |
| SCHEMBL7539088 | 0.89 | ITGB2 (0.52) | ITGB2ICAM1ITGALHDAC8HDAC3 | |
| SCHEMBL7540043 | 0.88 | TACR1 (0.46) | ITGB2ICAM1ITGALERAP2TACR1 | |
| SCHEMBL7540086 | 0.88 | ITGB2 (0.49) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |