3-Hydroxybenzaldehyde

3-Hydroxybenzaldehyde

SCHEMBL7545336

O=Cc1ccc(F)c(F)c1.O=Cc1cccc(O)c1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 1/20 0.49
CDK1 P06493 1/20 0.49
CDK4 P11802 1/20 0.49
CCNB1 P14635 1/20 0.49
CCND1 P24385 1/20 0.49
CCNB3 Q8WWL7 1/20 0.49
NFE2L2 Q16236 1/20 0.49
LCK P06239 2/20 0.44
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43
ERN1 O75460 1/20 0.43
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
AR P10275 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Hydroxybenzaldehyde SCHEMBL35726 0.84
3-Hydroxybenzaldehyde SCHEMBL29085774 0.84 CCNB2 (0.63) CCNB2CDK1CDK4CCNB1CCND1
3-Hydroxybenzaldehyde SCHEMBL29381261 0.84
3-Hydroxybenzaldehyde SCHEMBL29155378 0.82 CCNB2 (0.61) CCNB2CDK1CDK4CCNB1CCND1
3-Hydroxybenzaldehyde SCHEMBL29017504 0.82 CCNB2 (0.61) CCNB2CDK1CDK4CCNB1CCND1
3-Hydroxybenzaldehyde SCHEMBL28730066 0.82 CCNB2 (0.61) CCNB2CDK1CDK4CCNB1CCND1
3-Hydroxybenzaldehyde SCHEMBL9454352 0.82 CCNB2 (0.61) CCNB2CDK1CDK4CCNB1CCND1
3-Hydroxybenzaldehyde SCHEMBL31057906 0.82 CCNB2 (0.61) CCNB2CDK1CDK4CCNB1CCND1
SCHEMBL48607 0.82 ALDH1A1 (0.52) NFE2L2KDM4EPTGS2RAB9AALDH5A1
SCHEMBL29389102 0.82 ALDH1A1 (0.52) NFE2L2KDM4EPTGS2RAB9AALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214330-A1 BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION Bioscience AG (DE) 2002-06-19 EP disclosed
WO-2001021634-A1 BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-03-29 WO disclosed